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What does "somebody's to lose" mean? Is it a positive use? Does it mean that actually someone is going to win? Or does it mean that someone is gonna lose as literally stated?

For example, " this election is his to lose"
This sentence means he is gonna win or lose??

Also, then, what does " somebody's to gain" mean?
Thanks a lot.

"This election is his to lose."

I interpret that as saying that under normal circumstances, and according to all predictions, he will win the election. He will have to do something really stupid to lose it.

Same idea in the song "Mine To Lose".

Conversely, in "his to win/gain", he has to work hard to win.