Meaning: If you screw something up, you ruin it or you do it the wrong way.Synonym: muck up (informal), mess up, ruin
- screw up Louise really screwed up this time. We paid a lot for a fancy brochure about our seminar - and she put the wrong dates on it!
- screw sth up If she screws anything else up, she'll lose her job.
screw up: job, exam, test, interview, presentation, demonstration
When we told Louise that she'd screwed up the brochures, she was